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Diabetes Obes Metab 22(3):383392

doi: 10.1093/hmg/ddu328 49 FryALittlejohnsTJSudlowCDohertyNAdamskaLSprosenTet al

The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, decreased activity, incoordination, weight loss, convulsions, weakness, and salivation

These claims should be grounded in rigorous study designs, including clinical trials when available, and that regulatory status can vary by jurisdiction