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Anthony Didato, DMD Balanced Aesthetics + Wellness Leaky Gut (Intestinal Permeability) and Systemic Inflammation Increased intestinal permeability allows endotoxins (LPS) to enter the bloodstream, triggering systemic inflammatory cascades linked to anxiety, depression, brain fog, Frontiers in Immunology KPV Anti-Inflammatory Tripeptide From Alpha-MSH KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH) with potent anti-inflammatory properties

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Nuclear respiratory factors 1 and 2 (NRF1/NRF2) are transcription factors encoded in the nucleus signaling more than 250 genes

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