microdosing glp-1 for maintenance is popular, but there's little evidence it works What's the Deal with GLP-1

Safety & Side Effects Most common side effects are mild and transient: Mild increase in heart rate Nausea Decreased appetite Constipation or diarrhoea Fatigue In many cases, mild side effects from the drug can be temporary

Diabetes 61: 1250-1262, 2012

Although in those early studies, HDX was analyzed for insulin, -lactoglobulin, myoglobin, and poly-DL-alanine, because of the use of densitometry as analytical technique, the application of this method was limited by poor spatial resolution (early densitometric analysis measured average deuterium incorporation over large segments of a protein, which made it impossible to pinpoint specific sites of exchange)

Since compounding pharmacies mix the medication themselves, theres no guarantee that every batch has the same potency or effectiveness