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It is particularly effective when combined with another topical prescription medication, tretinoin, to enhance its absorption (and means that it can be applied once daily versus the normal twice daily application, and without the use of microneedle devices)

A noteworthy 2020 study employed the BTBR T + tf/J (BTBR) mouse model of idiopathic autism to assess the effects of curcumin treatment from PND 6 to PND 8

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