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The SURMOUNT 5 Trial: What the Numbers Actually Say SURMOUNT 5 enrolled 751 adults with obesity but without type 2 diabetes, randomized 1:1 to either tirzepatide (maximum tolerated dose of 10 or 15 mg) or semaglutide (maximum tolerated dose of 1.7 or 2.4 mg) for 72 weeks

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The timeline for appetite suppression varies from person to person depending on the dosage of the medication, individual metabolism, gender, body mass index, body composition, and other medications the patient is taking with semaglutide