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Immunohistochemical staining and western blot analysis revealed that SNL increased the activation of microglia and astrocytes in the dentate gyrus of the hippocampus, along with elevated expression of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6, which were significantly reversed by exendin-4 treatment [68]

Genetic testing for accurate diagnosis is made more favorable by the passing of the Genetic Information Nondiscrimination Act (GINA), which prohibits discrimination based on an individuals genetic information by employers and health insurers

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