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The IR-A isoform is most important in the processes of prenatal growth and development, whereas the IR-B isoform predominates in the metabolic processes regulated by insulin in the adult

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Mounjaro is a dual-targeting drug as it also targets the glucose-dependent insulinotropic polypeptide (GIP) receptor, making it the first-in-class GIP/GLP-1 receptor agonist for the treatment of type 2 diabetes

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