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1 The retrospective analysis looked at a prospectively designed observational registry from Fight Retinal Blindness

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To identify the central mechanisms of action, a group of rats was injected systemically with fluorescently labelled exenatide, which was shown to cross the bloodbrain barrier and bind putative GLP1 receptors expressed on dopamine D 1 and D 2 receptors, expressing GABAergic medium spiny neurons in the NAc shell (Zhang et al., 2020)