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GSH also detoxifies electrophilic xenobiotics compounds (chemical carcinogens, environmental pollutants, drugs, etc.) and their metabolites to GSH adduct (GS-X) in the direct catalysis of glutathione-S-transferase (GST, primary approach) [32]

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GHK-Cu also apparently increased glutathione (GSH) levels, suggesting a broader upregulation of antioxidant defense mechanisms rather than action through a single pathway