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In between-drug comparisons, tirzepatide at doses of 15 mg, 10 mg and 5 mg demonstrated greater efficacy than semaglutide at doses of 2.0 mg (MD = 4.60 kg [95% CI 7.94, 1.26]), 1.0 mg (MD = 3.53 kg [95% CI 4.80, 2.25]) and 0.5 mg (MD = 2.75 kg [95% CI 4.23, 1.28]), respectively (ESM Table 11)
Until now, however, neither of these two popular drugs have been covered by Medicare for weight loss, and theyve only rarely been covered by Medicaid, he said, adding, Theyve often cost consumers more than $1,000 per month, and some a lot more than that
The frequency and severity of these events may differ