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Various techniques, such as incorporating a cell-penetrating peptide (CPP) sequence or lipid conjugation, were employed to facilitate the intracellular delivery of the peptides 43

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MDSCs as pillars of immunosuppressive network MDSCs are critical components of the tumor microenvironment and play a pivotal role in the failure of various immunotherapeutic approaches, including ICIs, CAR-T, CAR-NK, CAR-NKT, CAR-macrophage (CAR-M), oncolytic virus, and cancer vaccine [10]