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Baseline cardiovascular assessment should include detailed history of prior cardiovascular events, current symptoms, blood pressure measurement, lipid profile, renal function assessment, and calculation of 10-year atherosclerotic cardiovascular disease (ASCVD) risk using validated tools such as the Pooled Cohort Equations

Set smaller, manageable goals instead of trying to change everything at once

Take levothyroxine first thing in the morning, wait at least 30 minutes, then take oral semaglutide

Perhaps you're changing jobs or making a significant lifestyle change and need a bit more control over when you take your dose