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Because NADPH is depleted on the same rapid time scale as L-cystine and L-cysteine accumulation (10 min), we hypothesized that the intracellular conversion of L-cystine to L-cysteine might drive glucose deprivation-induced NADPH depletion, ROS generation, and subsequent cell death

Questi risultati indicano che tutti i tessuti studiati hanno la capacit di convertire il TML in butirrobetaina attraverso il contenimento degli enzimi necessari ma, eccezion fatta per reni, fegato e cervello, non tutti possono convertire la butirrobetaina in carnitina

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