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Allicin induces the upregulation of ABCA1 expression via PPAR/LXR signaling in THP-1 macrophage-derived foam cells

A systematic review was consistent with our results: gastrointestinal toxicities tended to occur early after treatment initiation with fluctuation over time, both in a type 2 diabetic population and a more general population ( To further assess the severity of gastrointestinal AEs related to different GLP-1RAs, the severe proportion was compared among different GLP-1RA treatments

This change has the potential for far-reaching consequences for both regulatory agencies and employers