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10.1016/s0143-4160(02)00075-1 324 WariishiS.MiyaharaK.TodaK.OgoshiS.DoiY.OhnishiS.et al (1995)

30 In adolescents with obesity, semaglutide 2.4 mg once weekly led to weight loss similar to that observed in adults (a 16.1% mean reduction in BMI from baseline vs 0.6% with placebo at 68 weeks), along with improvements in cardiometabolic risk factors such as waist circumference, glycated haemoglobin (HbA 1c ), LDL-cholesterol, triglyceride and alanine transaminase levels