Chitosan (CS, low molecular weight, Sigma-Aldrich, USA), sodium tripolyphosphate (TPP, Na 5 P 3 O 10 , assay: 94%, Qualikems, India), GSH (C 10 H 17 N 3 O 6 S, assay: 95%, AKSCI, USA), and acetic acid (C 2 H 4 O 2 , assay: 99%, Alpha Chemicals, Cairo, Egypt)
Its essentially the same mechanism we see elsewhere in the body
Sorensen SA, Mulvihill JJ, Nielsen A
Three 20-week double-blind, placebo-controlled studies each with 34-week extensions were conducted to evaluate the efficacy and safety of sitagliptin in 410 pediatric patients aged 10 to 17 years with inadequately controlled type 2 diabetes, with or without insulin therapy (HbA1c 6.5-10% for patients not on insulin, HbA1c 7-10% for patients on insulin)