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(2021), which demonstrated significant activation of the TLR4/NF-B pathway in the endometrial tissue of PCOS patients ( 3.2 Exacerbation of insulin resistance Studies confirm that LPS and its induced inflammatory cytokines (e.g., TNF-) directly disrupt insulin signaling

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Hypoglycemia: While Semaglutides risk of hypoglycemia is lower when used alone (not with insulin or sulfonylureas), its blood sugar-lowering effects combined with the metabolic changes induced by Topiramate and significant weight loss necessitate vigilant blood sugar monitoring, especially in individuals with diabetes