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The nonclassical pyroptosis pathway is triggered by the direct sensing of lipid components, with caspase-4/5/11 detecting intracellular lipopolysaccharide (LPS) (101103)

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At 2.5 mg/mL, 1 mg = 0.40 mL = 40 units

Other studies report that the concentration of SCFAs, which is associated with a decreased abundance of Faecalibacterium, Enterococcus, Enterobacter, Bifidobacterium, Clostridium, Bacteroides, and Roseburia , is inversely correlated with the degree of renal insufficiency in patients (Wang et al., 2019