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Ethics declarations Funding The authors wish to thank Daniel Soares Freire, MD, PhD for providing medical writing and Cristiane Mapurunga Aoqui Guenoub, MD, PhD for providing assistance with English-language editing, both on behalf of Springer Healthcare

Session 1 After informed consent was obtained, participants completed a Timeline Follow Back (TLFB) to measure drinking in the past 30 days, Patient Health Questionnaire (PHQ-9), and a medical interview which asked about current and past medication history and other medical history to ensure safe participation in the study, as reviewed by a study physician

Without adequate acid, this step fails, and the B12 stays locked to the food, unable to be absorbed

So, how much is too much