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MBTPS1 (Membrane-bound transcription factor protease site 1) is a protease that functions on the endoplasmic reticulum membrane [29]

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Sisley S., Gutierrez-Aguilar R., Scott M., DAlessio D.A., Sandoval D.A., Seeley R.J

Cardiac hypertrophy leads to heart failure at the later decompensated stage of the disease process, which is a primary cause of morbidity and mortality