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Fibrosis alters IFP biomechanics, reducing its cushioning capacity and increasing mechanical stress on adjacent joint structures, thereby accelerating cartilage degeneration (Jeyaraman et al., 2022

It contains a group of compounds called silymarin, which helps the body naturally increase its own internal production of glutathione and prevents it from being depleted

TLR5 activation also contributes to transient lipid accumulation, which is essential for physiological liver regeneration

Furthermore, in the absence of Cu 2+ , the apoenzyme component of the active enzyme becomes non-functional, halting the synthesis of Cu-SOD