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Potential concerns and unknowns Several important unknowns remain regarding 5-amino-1mq safety

[119] conducted a phase II clinical trial in patients with NASH, that is, a placebo-controlled trial of subcutaneous sommarutide in the treatment of NASH, and found that sommarutide treatment resulted in a significantly higher proportion of patients in remission of NASH compared with placebo

In particular, the anterior cingulate cortex and frontal cortex manifest pathological changes across all symptoms covered in this review, marking them potentially critical regions for most AD-associated NPS