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Indeed, kidney secondary outcomes from CVOTs showed a decrease in albuminuria and in events related to decreased GFR when GLP-1 RAs were tested for T2DM (enrolling a majority of participants with overweight/obesity) or overweight/obesity without T2DM, as discussed below [26, 41, 48] (Table 3)

But we need to investigate further to determine whether factors such as the dose and duration of treatment may or may not lead to any differences in outcomes. Reference: Bariatric surgery is more cost effective than newer weight loss drugs alone

Acupuncture promotes muscle cells ATP metabolism in ST36 acupoint local exerting effect by activating TRPV1/CaMKII/AMPK/PGC1 signaling pathway

Therefore, given the retrospective nature of this study, the conclusions should be taken more conservatively