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In 2025, a joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society suggested that patients on GLP-1 drugs consider a multivitamin-mineral supplement, flagging nutrients of concern including vitamin D, B12, iron, calcium, magnesium, and zinc

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Consequently, NAD infusion is used in the treatment of neurodegenerative disorders as well as addiction recovery

These models could further be leveraged to investigate if NSC-secreted factors modulate the gut microbiomes metabolic output or vice versa, providing a mechanistic link between the central and peripheral effects observed in our study