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These results encouraged the possibility that a clinically useful drug could be designed possessing oral efficacy, increased metabolic stability, and BBB penetrability offering facilitated cognitive functioning

Standard Mounjaro Side Effects: Nausea, vomiting, diarrhoea, constipation, reduced appetite, and abdominal discomfort are common when starting or increasing doses

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Research aims to determine whether GLP-3 causes similar GI side effects as GLP-1, if tolerability differs between the peptides, what optimal dosing strategies minimize side effects, and if GLP-3 might suit patients who dont tolerate GLP-1 agonists well