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The rhomboid minor is the smaller muscle positioned above its larger partner, the rhomboid major

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In addition to multifocal lesions in MS, in a recent study using fluorescence spectroscopy using the solvatochromic lipid probe Nile Red, we reported diffuse changes in myelin lipid polarity in otherwise normal-appearing MS white matter, which was particularly pronounced in the periventricular areas, again supporting the notion of a myelin toxin circulating in the CSF