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What Caffeine Actually Does in the Brain Caffeine is a stimulant

doi: 10.1021/tx800368n

Eating behaviorincluding meal timing, food reward, satiety responsiveness, and even mindful eatingcan impact the release and activity of GLP-1 (Huber et al 2024)

Fatigue followed a similar dose-dependent pattern, ranging from near 0% at the lowest dose to about 46% in some higher-dose arms, compared with about 13% in the semaglutide arm of STEP 3