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The IHC and IF images were captured using a Keyence microscope (BZ-X800E

Mechanisms deciphered in these studies indicate that the interaction between serotonin and GLP-1 in the hindbrain increases proopiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) neuron activity, leading to induction of satiety signals and suppression of neuropeptide Y/agouti-related peptide (NPY/AgRP) neuron activity, which in turn suppresses hunger

For example, higher GLP-1R expression was significantly associated with longer DFS in LGG patients (HR = 0.30, p = 5.6491e-03), whereas stomach adenocarcinoma (STAD) patients had shorter DFS with increased GLP-1R expression (HR = 1.90, p = 2.9621e-02) (Fig

doi: 10.1016/S0196-9781(99)00208-9 85 SgambatoSPassarielloNPaolissoGMaranoABuonincontiRTesauroP