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GLP-1 drugs work for most people, but some lose more weight than others, and not everyone has the same results

Notably, patients with metabolic syndrome or T2DM exhibit abnormal enlargement and biotransformation of EAT and experience higher relative event rates compared to obese individuals with lower EAT volume (109)

Most people benefit from supplementation while on GLP-1 medications because reduced food intake makes it harder to meet daily protein and micronutrient needs through diet alone

For type 2 diabetes and long-term weight management, the recommended maintenance dose is 5 mg, 10 mg, or 15 mg, administered subcutaneously once weekly