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FIGURE 2 Effects of Oxidative Stress on Inflammation in the Ovaries Inflammation and Ovarian Aging Inflammation is associated with the pathogenesis of human aging (Lpez-Otn et al., 2013

10.1089/ten.1999.5.127 138 TarnawskiA

Youll find: A red velvet sofa that brings warmth and softness A worn piano and scattered vinyl records Wine glasses , instruments, and tiny personal touches that hint at a song just ending Golden lamps that fill the room with gentle light A vintage lift resting in the corner A small balcony overlooking the quiet rooftops And through the tall window, the Eiffel Tower glowing at midnight None of these elements recreate one exact place in Paris, but together they rebuild the emotion of that experiencewarm, nostalgic, and quietly romantic

In type 2 diabetes, glutathione depletion exacerbates hyperglycemia-induced ROS production, creating a feed-forward loop in which oxidative stress both results from and worsens insulin resistance (9)