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Izuta Y, Imada T, Hisamura R, Oonishi E, Nakamura S, Inagaki E, Ito M, Soga T, Tsubota K (2018) Ketone body 3-hydroxybutyrate mimics calorie restriction via the Nrf2 activator, fumarate, in the retina

recently published an article where oral glutathione ingestion was shown to be successful in raising body stores of glutathione

No single compound modulates all of these processes simultaneously

More generally, how p53 pathway-dependent regulation of nucleotide metabolism links to the broader control of cell fate by p53 requires more detailed investigation