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Key characteristics of allulose include: Minimal caloric contribution Does not meaningfully raise blood glucose or insulin levels Substantial absorption with urinary excretion of unchanged allulose Natural occurrence in select foods Understanding these fundamental properties is essential when considering allulose's potential interactions with metabolic pathways, including those involving incretin hormones such as glucagon-like peptide-1 (GLP-1)

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Although IL18 is a common ligand for IL18R1, in this study, IL18R1 could also be bound by CXCL10

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