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Description

GLP-1 receptor agonists including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have produced some of the most dramatic weight loss outcomes in the history of pharmacology

To test this hypothesis, a subgroup of HFD mice, randomly chosen 1 week before PDAC organoid engraftment, were treated with 30 nmol/kg SEMA (SEMA mice