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GLP1 medicines help people eat less, not by willpower, but by changing how their bodies and brains work
300,301 This not only affects the intracellular signaling of macrophages but also their response to the external environment, including their effects on chondrocytes and other synovial cells
Daniel Drucker, one of the pioneers in GLP-1 research, put it perfectly: Theres something about GLP-1 that mitigates a lot of chronic diseases that people have, and we really need to understand better how that works. Studies appearing in multiple journals have demonstrated these drugs possess systemic anti-inflammatory and cardioprotective effects
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