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The best characterized, classic form of SPIGFD is Laron syndrome, caused by mutations in the GHR gene [12, 13]

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The fifth group, pre-cultured in hypoxia, was incubated with 30% H 2 O 2 in the last 1 h to mimic a quick hypoxia recovery, then incubated with PBS for 30 min and DSNBD-GSH (10 M) for 30 min and imaged

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