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For immunofluorescence, the next day, the secondary antibody and 4,6-diamino-2-phenylpyridine (DAPI) nuclear stain were applied to the paraffin sections, which were then mounted with an anti-quenching solution

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After several years of research on biological therapies and small molecules to target inflammation, we need a different strategy to further get more insights into mechanisms underlying rheumatoid arthritis pathogenesis and identify potential new treatments, as a significant proportion of patients are partial responders

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