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The major obstacles to developing probes that can monitor GSH dynamics include the reaction reversibility and kinetics of the sensing reaction, as well as the high abundance of GSH (110 mM) inside cells

Although ferroptosis is typically induced under conditions of intracellular iron overload, compromised antioxidant capacity, and elevated oxidative stress, endometriotic lesions exhibit an iron-rich microenvironment in which cells paradoxically display increased resistance to ferroptosis, thereby facilitating their survival, progression, and establishment [15]

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