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Targeted methods using multiple reaction monitoring (MRM) on a triple quadrupole platform were also developed by quantitatively labeling all available cysteine residues with a labeling reagent yielding isomerically-modified peptides following enzymatic digestion

fermentum A51 carried genes encoding thioredoxin reductase ( NADPH ), glutathione reductase, peptide methionine sulfoxide reductase msrA/msrB ( msrA , msrB ), thiol peroxidase ( tps ) and thioredoxin 1 ( trsX ) (Table 6), implying that L