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Furthermore, mRNA and protein expression of CCL11 were both downregulated after GSDMD knockdown in THP-1 cells, suggesting that the absence of GSDMD not only reduced the release of CCL11 through pyroptosis process but also directly inhibited the CCL11 production

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Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension