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Only a small, yet significant amount is metabolised via the hepatic cytochrome P450 enzyme system (its CYP2E1 and CYP1A2 isoenzymes), which is responsible for the toxic effects of paracetamol due to a minor alkylating metabolite (N-acetyl-p-benzo-quinone imine, abbreviated as NAPQI).[17] There is a great deal of polymorphism in the P450 gene, and genetic polymorphisms in CYP2D6 have been studied extensively

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If it's low enough, it's not a big deal, but if you over-consume, of course, it's a problem

The condition affects the extensor tendons that attach to the lateral epicondyle, the bony prominence on the outside of your elbow