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A commenter recommended that CMS adopt and re-specify the MSK-3 measure for this measure set, noting that the MSK-3 measure utilizes PROMIS Pain Interference, which would offer significant benefits, such as enabling cross-cutting comparability of results across diverse patient populations and care settings that are not limited solely to low back pain

Neither approach has demonstrated clear superiority in research studies

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Dosage Protocols Beginner (Weeks 1-2) Dose : 150 mcg subQ Timing : Morning, fasted Frequency : Once daily Adaptation minimizes side effects