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Previous studies in preclinical models demonstrate the potential for GcgR agonism to induce weight loss either alone [54,55] or in combination with GLP-1R and/or GIPR agonism [43]

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Again, this solubility (for the AK Sci niclosamide) was measured to be only 1.77uM 1uM, and so is actually in good agreement with van Tonder and de Villiers (21)