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(2011) Nat.Chem.Biol

Spermidine synthase is encoded by the SRM gene (also known as SPDSY) which is located on chromosome 1p36.22 and is composed of 8 exons that encode a protein of 302 amino acids

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Regarding cardiac risk, the lorcaserin group was non-inferior to the placebo group with slightly better values in cardiac risk factors (blood pressure, heart rate, glycemic control, lipid profile)