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NAFLD is associated with metabolic syndromes and the incidence of NAFLD has increased over time [4, 5]

The potential biological mechanisms underlying their influence on cancer risk are complex, involving metabolic regulation, direct antitumor effects, immune modulation, and epigenetic changes

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It has been hypothesized that G6PD deficiency confers a selective advantage against malaria, as there is substantial overlap of G6PD deficiency prevalence in regions of historical malaria-endemicity ( 2 Importance of G6PD for innate immunity G6PD and the PPP are crucial for innate immune system function