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Higher-risk elective patients For patients at higher risk, management should be individualized
Its best to use one of the following areas (see Figure 1): Your abdomen (belly), except for the 2-inch (5-centimeter) area around your belly button The middle front or middle outside of your thighs The upper area of your buttocks (butt) The back part of your upper arms, if someone else is giving you the injection If your healthcare provider tells you to use a certain injection site, follow their instructions
The R311C mutant also exerts a dominant-negative effect over wild-type CaMKK2 in heterozygous carriers
Preserved access to clinically appropriate therapies
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