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Gastrointestinal side effects such as nausea, vomiting, and diarrhoeawhich are very common with GLP-1 receptor agonists according to the SmPCcan lead to dehydration and secondary thirst

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Of these, 58 patients required hospitalization, 4 of whom ended up in the intensive care unit (ICU)

While the exact mechanisms driving these benefits remain unclear, they likely involve diverse effects, including anti-inflammatory properties and mitigation of oxidative stress [52]