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Supplementation of vitamin B12 COMPOSITION Cyanocobalamin (Vitamin B12) 1mg/mL ACTIONS Supplementation of Vitamin B12 INDICATIONS Vitamin B12 supplement for the treatment of macrocytic anaemia in horses and dogs DOSAGE AND ADMINISTRATION Administer intramuscularly twice weekly or as directed by a veterinary surgeon

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The specific verification process was as follows: 1) PGC-1siRNA knockdown resulted in decreased expression of antioxidant proteins under VOA treatment, and subsequently increased intracellular ROS level after H 2 O 2 stress