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Furthermore, the PfGrx-catalyzed oxidation of roGFP2 is more than four orders of magnitude faster than the uncatalyzed reaction with GSSG and occurs two orders of magnitude faster via the glutathione-dependent monothiol mechanism than by the glutathione-independent dithiol mechanism (Fig

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Ying Tian, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Cell Death and Survival, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers