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Alternative treatment options vary by concern being treated

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Despite the developments in ML, the interpretability of complex models and the need for validation in various patient populations pose challenges

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Angiogenesis & perfusion: Endothelial tube formation and improved blood-flow recovery after ischemia described via VEGFR2-Akt-eNOS signaling (Hsieh 2017)

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It is not known if DUPIXENT is safe and effective in children with BP under 18 years of age

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