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If you cut back too drastically on your food intake, especially protein, your body will break down muscle for fuel
then, the penetration depth of the drug in the skin tissue is limited, and the drug delivery efficiency can be improved by increasing the penetration depth of the drug in the dermis layer of the adipose tissue through INT technology
Gradual dose titration is recommended to account for interindividual variability and minimize side effects such as sleep changes or gastrointestinal discomfort (Kim et al., 2020)
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